Product Name: SAE1 Antibody, Rabbit PAb, Antigen Affinity Purified
Immunogen: Recombinant Human SAE1 protein
Mouse IgG1: Rabbit IgG
Concentration:
Formulation: 0.2 μm filtered solution in PBS
Preparation: Produced in rabbits immunized with purified, recombinant Human SAE1 . SAE1 specific IgG was purified by Human SAE1 affinity chromatography.
Specificity: Human SAE1
Application: WB, ELISA, IPWB: 5-10 μg/mLELISA: 0.1-0.2 μg/mLThis antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human SAE1. The detection limit for Human SAE1 is < 0.039 ng/well.IP: 0.5-2 μg/mg of lysate
CAS NO.: 38194-50-2
Product: Sulindac
Storage: This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.Sodium azide is recommended to avoid contamination (
Caption:
Background: SAE1 belongs to the ubiquitin-activating E1 family. It is a heterodimer that acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It functions as a UBLI E1 ligase mediating the ATP-dependent activation of UBL1. SAE1 binds with UBLE1A and UBLE1
PubMed ID:http://jpet.aspetjournals.org/content/241/1/251