D or vicarious stigma–plays a role in rural communities’ experiences with discrimination toward PLWHA (or those who are perceived to be PLWHA) because of their membership or perceived membership in other discriminated groups. The following quotation reflects the relationship Z-DEVD-FMKMedChemExpress Z-DEVD-FMK between perceptions of who is at risk (cause) and HIV-infected groups that are discriminated against (experienced or vicarious stigma): And he act bi-sexual. He act gay. No offense to anyone, but he really didn’t get into how he got it but I’m thinking, you know, by [being] gay or him just being bi-sexual would put him at risk. (PLWHA participant) Felt normative stigma and lack of disclosure are related consequences of HIV stigma for PLWHA in the following quotation example:NIH-PA Author Manuscript NIH-PA Author Manuscript NIH-PA Author ManuscriptN C Med J. Author manuscript; available in PMC 2011 February 11.Sengupta et al.Cycloheximide price PageAnd it was always the same story. People would rather die and cover it up [HIV/ AIDS] than to expose themselves to ridicule, `cause there’s nobody to actually counsel them. (PLWHA participant) Lack of disclosure could also be directly affected by causes of HIV stigma, such as lack of knowledge about HIV among loved ones within the community: My family and friends and my church family because they’re, like I said, unknowledgeable of it [HIV/AIDS] so I keep it hid…I would let whoever know not to bring it up around my family or whoever because they…it’s lack of knowledge of it. (PLWHA participant) Since the first phase of our project was to understand the feasibility of implementing HIV clinical trials in rural communities–using either a standing clinic or mobile unit–some of our questions focused on what may make it difficult to implement clinical trials locally. The themes elicited from this inquiry were considered to be more reflective of the consequences of HIV stigma and associated with non-disclosure. As an example, the following quotation illustrates the concern over protecting confidentiality when using a mobile van to conduct HIV clinical trials: I guess it would be okay for people if they really didn’t mind people knowing what was going on. `Cause I don’t see how, I mean to me that’s going back to confidentiality. I mean if there’s a van parked somewhere…I could hear people now, “what is that van for?” or “why you going to that van?” And so it’s just like you’re opening yourself up. So me personally, I wouldn’t [go]. (PLWHA participant) A community leader focus group participant echoed similar issues with using a mobile van: Once it comes in once or twice…people are going to know the van…And then if they know oh that’s [the] AIDS [van] well…”Why is he getting in that? He must have AIDS. Let’s go tell the neighbors.” For some, local implementation of HIV clinical trials may not be feasible because of potential breaches in confidentiality. When asked about their preferences of where to go to participate in HIV clinical trials, a PLWHA participant stated: I would prefer to go to University [A] `cause I wouldn’t want to participate in nothing in my own, oh no, not in my own community, no sir…Because folks talk so much and ohhh, I could see my name around, oh no…I would go out of town where nobody didn’t know me…And then I wouldn’t have to worry about it being exposed.NIH-PA Author Manuscript NIH-PA Author Manuscript NIH-PA Author ManuscriptNot reflected in Figure 1, but important because it identifies countering strate.D or vicarious stigma–plays a role in rural communities’ experiences with discrimination toward PLWHA (or those who are perceived to be PLWHA) because of their membership or perceived membership in other discriminated groups. The following quotation reflects the relationship between perceptions of who is at risk (cause) and HIV-infected groups that are discriminated against (experienced or vicarious stigma): And he act bi-sexual. He act gay. No offense to anyone, but he really didn’t get into how he got it but I’m thinking, you know, by [being] gay or him just being bi-sexual would put him at risk. (PLWHA participant) Felt normative stigma and lack of disclosure are related consequences of HIV stigma for PLWHA in the following quotation example:NIH-PA Author Manuscript NIH-PA Author Manuscript NIH-PA Author ManuscriptN C Med J. Author manuscript; available in PMC 2011 February 11.Sengupta et al.PageAnd it was always the same story. People would rather die and cover it up [HIV/ AIDS] than to expose themselves to ridicule, `cause there’s nobody to actually counsel them. (PLWHA participant) Lack of disclosure could also be directly affected by causes of HIV stigma, such as lack of knowledge about HIV among loved ones within the community: My family and friends and my church family because they’re, like I said, unknowledgeable of it [HIV/AIDS] so I keep it hid…I would let whoever know not to bring it up around my family or whoever because they…it’s lack of knowledge of it. (PLWHA participant) Since the first phase of our project was to understand the feasibility of implementing HIV clinical trials in rural communities–using either a standing clinic or mobile unit–some of our questions focused on what may make it difficult to implement clinical trials locally. The themes elicited from this inquiry were considered to be more reflective of the consequences of HIV stigma and associated with non-disclosure. As an example, the following quotation illustrates the concern over protecting confidentiality when using a mobile van to conduct HIV clinical trials: I guess it would be okay for people if they really didn’t mind people knowing what was going on. `Cause I don’t see how, I mean to me that’s going back to confidentiality. I mean if there’s a van parked somewhere…I could hear people now, “what is that van for?” or “why you going to that van?” And so it’s just like you’re opening yourself up. So me personally, I wouldn’t [go]. (PLWHA participant) A community leader focus group participant echoed similar issues with using a mobile van: Once it comes in once or twice…people are going to know the van…And then if they know oh that’s [the] AIDS [van] well…”Why is he getting in that? He must have AIDS. Let’s go tell the neighbors.” For some, local implementation of HIV clinical trials may not be feasible because of potential breaches in confidentiality. When asked about their preferences of where to go to participate in HIV clinical trials, a PLWHA participant stated: I would prefer to go to University [A] `cause I wouldn’t want to participate in nothing in my own, oh no, not in my own community, no sir…Because folks talk so much and ohhh, I could see my name around, oh no…I would go out of town where nobody didn’t know me…And then I wouldn’t have to worry about it being exposed.NIH-PA Author Manuscript NIH-PA Author Manuscript NIH-PA Author ManuscriptNot reflected in Figure 1, but important because it identifies countering strate.