RiationMaterials 2021, 14,ten of14, x FOR PEER REVIEWsamples. Compared to the typical sample
RiationMaterials 2021, 14,10 of14, x FOR PEER REVIEWsamples. In comparison with the normal sample R, the values of the hydration degree (Ha) increased significantly less in the case of the sample with gentamicin (GM sample). The largest amount of water is subsequently absorbed for the duration of the initial 7 days just after immersion; the values stay pretty much continuous within the case with the reference R, GM, and HUM samples. A variation is observed in the case of samples containing silver nanoparticles inside a dose-dependent 11 of 19 manner. Soon after exposure with the investigated bone cement samples to distilled water, no important transform in their IEM-1460 medchemexpress structure was observed (Figure five).FigureFigure 5. Morphological elements revealed by SEM and elemental surface analysis by EDS of21 days in 5. Morphological elements revealed by SEM and elemental surface evaluation by EDS from the samples immediately after the distilled water. just after 21 days in distilled water. samples3.4. Degradation Degree 3.four. Degradation Degree Figure six shows Figure 6 shows the variation in the variation of therate (DR) more than a (DR) over a period of 28 days within the degradation degradation price period of 28 days in simulated body fluid (SBF) at a temperature of 37 C, for the investigated bone cements simulated physique fluid (SBF) at a temperature of 37 , for the investigated bone cements samples. Right after 28 days of exposure to SBF resolution, the slight weight losses were observed samples. Immediately after 28 for GM samples, though the option, sample (R) weight losses degradation rate (DR). An days of exposure to SBF reference the slight includes a constant have been observed for GM samples, whilst the reference sample (R) has a constant degradation ratepeppermint crucial enhance in the degradation rate was observed for samples containing (DR). An increase within the degradation price was observed for samples containing some particlesessen-have been oil as additive. Following the exposure for the SBF answer, peppermint could removed from the matrix of for the SBF solution, some particles a reduction tial oil as additive. Following the exposurebone cements or Goralatide site dissolved, which led tocould have in weight. Within the matrix of bone cements or dissolved, which as much as 28 days, no in been removed from the case of samples containing silver nanoparticles, led to a reduction degradation process is observed, but only a continuous absorptionto 28 days, no degradaweight. Inside the case of samples containing silver nanoparticles, up course of action. tion course of action is observed, but only a continuous absorption process.OR PEER Components 2021, 14, 7031 REVIEW12 of 1911 ofDegradation price [ ] 3.0 2.five two.0 1.5 1.0 0.five 0.0 -0.five -1.R GM HUM AM1 AMDR [ ]1 0.0954 0.0969 0.1835 0.0000 -0.three 0.0838 0.0864 0.1826 -0.0915 -0.5 0.0895 0.0887 0.1830 -0.1791 -0.7 0.0918 0.1054 0.3660 -0.2503 -0.14 0.0940 0.1929 0.9107 -0.1807 -0.21 0.0918 0.2712 two.1478 -0.1885 -0.28 0.0929 0.2814 2.4713 -0.2967 -0.Time [days]Figure 6. Variation of degradation rate overof 28 days inof 28at 37 C, for experimental PMMA bone cements. Figure six. Variation of degradation rate over a period a period SBF, days in SBF, at 37 , for experimental PMMA bone cements.Exposure of your investigated bone cement samples to the SBF answer did not significantly influence their structure. EDS evaluation showed the presence of C, O, S, and Ba Exposure from the investigated bone cement samples towards the SBF resolution did not signif(Figure 7). icantly have an effect on their structure.results evaluation for the hydration degree of C,and S, and Ba (Figure (DR) The EDS recorded showed.