Product Name :
Nerigliatin
CAS No.:
1245603-92-2
Purity :
99.78%
Shipping:
Room temperature in the continental U.S. Other areas may vary.
Storage :
Powder: -20°C, 3 years; 4°C, 2 yearsIn solvent: -80°C, 6 months; -20°C, 1 month
SMILES:
O=C(C1=NC=C(OC2=C3C=C(C)OC3=CC(C(NC4=NC=C(C)N=C4)=O)=C2)C=N1)N(C)C
Product Description :
Nerigliatin (PF-04937319) is a glucokinase activator (GKA) with EC50 value of 154.4 ?μM, one of the most promising strategies for the treatment of type 2 diabetes mellitus.Nerigliatin is designed to maintain glucose-lowering efficacy while mitigating the risk of hypoglycaemia observed with many other GKAs.
Formula:
C22H20N6O4
Molecular Weight :
432.43
Synonyms:
PF-04937319
Additional Information:
|CAS No. 1245603-92-2 ; |Synonyms PF-04937319 ; |Formula C22H20N6O4 ; |Molecular Weight 432.43 ; |SMILES O=C(C1=NC=C(OC2=C3C=C(C)OC3=CC(C(NC4=NC=C(C)N=C4)=O)=C2)C=N1)N(C)C ; |Target Glucokinase ; |Product Description Nerigliatin (PF-04937319) is a glucokinase activator (GKA) with EC50 value of 154.4 ?μM, one of the most promising strategies for the treatment of type 2 diabetes mellitus.{{Trastuzumab emtansine} MedChemExpress|{Trastuzumab emtansine} Protein Tyrosine Kinase/RTK|{Trastuzumab emtansine} Technical Information|{Trastuzumab emtansine} Purity|{Trastuzumab emtansine} custom synthesis|{Trastuzumab emtansine} Autophagy} Nerigliatin is designed to maintain glucose-lowering efficacy while mitigating the risk of hypoglycaemia observed with many other GKAs.{{Amikacin} MedChemExpress|{Amikacin} Antibiotic|{Amikacin} Biological Activity|{Amikacin} In stock|{Amikacin} supplier|{Amikacin} Epigenetics} ; |Format Solid ; |Color White to yellow ; |Purity 99.PMID:24957087 78% ; |Shipping Room temperature in the continental U.S. Other areas may vary. ; |Storage Powder: -20°C, 3 years; 4°C, 2 yearsIn solvent: -80°C, 6 months; -20°C, 1 month ; |Solubility Overview Soluble in DMSO