Product Name :
Omipalisib (GSK2126458, GSK458)
CAS No.:
1086062-66-9
Purity :
> 99%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
COC1=NC=C(C=C1N[S](=O)(=O)C2=CC=C(F)C=C2F)C3=CC=C4N=CC=C(C5=CC=NN=C5)C4=C3
Product Description :
Omipalisib (GSK2126458, GSK458) is a highly selective and potent inhibitor of p110α/β/δ/γ, mTORC1/2 with Ki of 0.{{Danuglipron} medchemexpress|{Danuglipron} GCGR|{Danuglipron} Purity & Documentation|{Danuglipron} In Vivo|{Danuglipron} manufacturer|{Danuglipron} Epigenetic Reader Domain} 019 nM/0.13 nM/0.024 nM/0.06 nM and 0.18 nM/0.3 nM in cell-free assays, respectively. Phase 1.
Formula:
C25H17F2N5O3S
Molecular Weight :
505.5
Synonyms:
Additional Information:
|CAS No.{{Neratinib} MedChemExpress|{Neratinib} Protein Tyrosine Kinase/RTK|{Neratinib} Technical Information|{Neratinib} In Vivo|{Neratinib} custom synthesis|{Neratinib} Autophagy} 1086062-66-9 ; |Formula C25H17F2N5O3S ; |Molecular Weight 505.PMID:24761411 5 ; |SMILES COC1=NC=C(C=C1N[S](=O)(=O)C2=CC=C(F)C=C2F)C3=CC=C4N=CC=C(C5=CC=NN=C5)C4=C3 ; |Target p110α/β/δ/γ, mTORC1/2 ; |Product Description Omipalisib (GSK2126458, GSK458) is a highly selective and potent inhibitor of p110α/β/δ/γ, mTORC1/2 with Ki of 0.019 nM/0.13 nM/0.024 nM/0.06 nM and 0.18 nM/0.3 nM in cell-free assays, respectively. Phase 1. ; |Purity > 99% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO