Product Name :
(S)-CFT7455
Description:
(S)-CFT7455 is an orally active zinc finger transcription factors Ikaros (IKZF1), Aiolos (IKZF3) degrader. (S)-CFT7455 is an anti-cancer agent that binds with high affinity to the cereblon E3 ligase (Kd of 0.9 nM)(WO2022032132A1; Compound 1).
CAS:
2504235-67-8
Molecular Weight:
469.53
Formula:
C28H27N3O4
Chemical Name:
Smiles :
O=C1CC[C@@H](C(=O)N1)N1C2=CC=C(CC3=CC=C(CN4CCOCC4)C=C3)C3=CC=CC(=C23)C1=O
InChiKey:
MUKCJOOKCZSQNW-DEOSSOPVSA-N
InChi :
InChI=1S/C28H27N3O4/c32-25-11-10-24(27(33)29-25)31-23-9-8-20(21-2-1-3-22(26(21)23)28(31)34)16-18-4-6-19(7-5-18)17-30-12-14-35-15-13-30/h1-9,24H,10-17H2,(H,29,32,33)/t24-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
(S)-CFT7455 is an orally active zinc finger transcription factors Ikaros (IKZF1), Aiolos (IKZF3) degrader. (S)-CFT7455 is an anti-cancer agent that binds with high affinity to the cereblon E3 ligase (Kd of 0.9 nM)(WO2022032132A1; Compound 1).|Product information|CAS Number: 2504235-67-8|Molecular Weight: 469.53|Formula: C28H27N3O4|Smiles: O=C1CC[C@@H](C(=O)N1)N1C2=CC=C(CC3=CC=C(CN4CCOCC4)C=C3)C3=CC=CC(=C23)C1=O|InChiKey: MUKCJOOKCZSQNW-DEOSSOPVSA-N|InChi: InChI=1S/C28H27N3O4/c32-25-11-10-24(27(33)29-25)31-23-9-8-20(21-2-1-3-22(26(21)23)28(31)34)16-18-4-6-19(7-5-18)17-30-12-14-35-15-13-30/h1-9,24H,10-17H2,(H,29,32,33)/t24-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: To be determined|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Natalizumab (Solution)} MedChemExpress|{Natalizumab (Solution)} Integrin|{Natalizumab (Solution)} Biological Activity|{Natalizumab (Solution)} Data Sheet|{Natalizumab (Solution)} manufacturer|{Natalizumab (Solution)} Cancer} |Shelf Life: ≥12 months if stored properly.{{Olaratumab} site|{Olaratumab} Protein Tyrosine Kinase/RTK|{Olaratumab} Biological Activity|{Olaratumab} References|{Olaratumab} custom synthesis|{Olaratumab} Autophagy} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:24257686 |Drug Formulation: To be determined|HS Tariff Code: 382200|References:|David Proia, et al. Advantageous therapies for disorders mediated by ikaros or aiolos. WO2022032132A1.Products are for research use only. Not for human use.|