Product Name :
OSI-027
CAS No.:
936890-98-1
Purity :
> 97%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
COC1=CC=CC2=C1[NH]C(=C2)C3=C4[N](N=CN=C4N)C(=N3)C5CCC(CC5)C(O)=O
Product Description :
OSI-027 is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM in cell-free assays, and more than 100-fold selectivity observed for mTOR than PI3Kα, PI3Kβ, PI3Kγ or DNA-PK.{{Certolizumab pegol} MedChemExpress|{Certolizumab pegol} TNF Receptor|{Certolizumab pegol} Biological Activity|{Certolizumab pegol} Data Sheet|{Certolizumab pegol} custom synthesis|{Certolizumab pegol} Autophagy} Phase 1.{{Bliretrigine} site|{Bliretrigine} Sodium Channel|{Bliretrigine} Purity & Documentation|{Bliretrigine} In stock|{Bliretrigine} custom synthesis|{Bliretrigine} Epigenetic Reader Domain}
Formula:
C21H22N6O3
Molecular Weight :
406.PMID:23291014 44
Synonyms:
ASP4786
Additional Information:
|CAS No. 936890-98-1 ; |Synonyms ASP4786 ; |Formula C21H22N6O3 ; |Molecular Weight 406.44 ; |SMILES COC1=CC=CC2=C1[NH]C(=C2)C3=C4[N](N=CN=C4N)C(=N3)C5CCC(CC5)C(O)=O ; |Target mTOR ; |Product Description OSI-027 is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM in cell-free assays, and more than 100-fold selectivity observed for mTOR than PI3Kα, PI3Kβ, PI3Kγ or DNA-PK. Phase 1. ; |Purity > 97% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO