Product Name :
Bisdionin C
Description:
Bisdionin C is a potent GH18 chitinases inhibitor, with an IC50 of 0.2 μM for A. fumigatus ChiB1 (AfChiB1). Bisdionin C inhibits HCHT (human macrophage chitotriosidase) and acidic mammalian chitinase (AMCase) with IC50s of 8.3 and 3.4 μM, respectively.
CAS:
74857-22-0
Molecular Weight:
400.39
Formula:
C17H20N8O4
Chemical Name:
1-[3-(3,7-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl)propyl]-3,7-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
Smiles :
CN1C=NC2=C1C(=O)N(CCCN1C(=O)N(C)C3N=CN(C)C=3C1=O)C(=O)N2C
InChiKey:
KEPIKAFUZRKZMT-UHFFFAOYSA-N
InChi :
InChI=1S/C17H20N8O4/c1-20-8-18-12-10(20)14(26)24(16(28)22(12)3)6-5-7-25-15(27)11-13(19-9-21(11)2)23(4)17(25)29/h8-9H,5-7H2,1-4H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Bisdionin C is a potent GH18 chitinases inhibitor, with an IC50 of 0.2 μM for A. fumigatus ChiB1 (AfChiB1). Bisdionin C inhibits HCHT (human macrophage chitotriosidase) and acidic mammalian chitinase (AMCase) with IC50s of 8.3 and 3.4 μM, respectively.|Product information|CAS Number: 74857-22-0|Molecular Weight: 400.39|Formula: C17H20N8O4|Chemical Name: 1-[3-(3,7-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl)propyl]-3,7-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione|Smiles: CN1C=NC2=C1C(=O)N(CCCN1C(=O)N(C)C3N=CN(C)C=3C1=O)C(=O)N2C|InChiKey: KEPIKAFUZRKZMT-UHFFFAOYSA-N|InChi: InChI=1S/C17H20N8O4/c1-20-8-18-12-10(20)14(26)24(16(28)22(12)3)6-5-7-25-15(27)11-13(19-9-21(11)2)23(4)17(25)29/h8-9H,5-7H2,1-4H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Nonyl β-D-glucopyranoside} MedChemExpress|{Nonyl β-D-glucopyranoside} {Biochemical Assay Reagents}|{Nonyl β-D-glucopyranoside} Protocol|{Nonyl β-D-glucopyranoside} Formula|{Nonyl β-D-glucopyranoside} custom synthesis|{Nonyl β-D-glucopyranoside} Autophagy} |Shelf Life: ≥12 months if stored properly.{{Darinaparsin} MedChemExpress|{Darinaparsin} Apoptosis|{Darinaparsin} Biological Activity|{Darinaparsin} In Vivo|{Darinaparsin} custom synthesis|{Darinaparsin} Autophagy} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23514335 |Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|