Product Name :
IFN alpha-IFNAR-IN-1 hydrochloride
Description:
IFN alpha-IFNAR-IN-1 hydrochloride is a nonpeptidic, low-molecular-weight inhibitor of the interaction between IFN-α and IFNAR; inhibit MVA-induced IFN-α responses by BM-pDCs (IC50=2-8 uM). IC50 value: Target: IFN alpha-IFNAR interaction inhibitor IFN alpha-IFNAR-IN-1 specifically inhibits MVA-induced IFN-α responses by BM-pDCs. IFN alpha-IFNAR-IN-1 inhibited the IFN-α responses that were elicited after treatment with CpG2216, stimulation with poly(I:C), and infection with VSV-M2, whereas the total IL-12 production was notably less affected under those conditions. IFN alpha-IFNAR-IN-1 exerts immunosuppressive activity by the direct interaction with IFN-α .
CAS:
2070014-98-9
Molecular Weight:
315.{{Valrubicin} MedChemExpress|{Valrubicin} PKC|{Valrubicin} Purity & Documentation|{Valrubicin} In stock|{Valrubicin} custom synthesis|{Valrubicin} Autophagy} 86
Formula:
C18H18ClNS
Chemical Name:
N-methyl-1-(2-(naphthalen-1-ylthio)phenyl)methanamine hydrochloride
Smiles :
Cl.CNCC1=CC=CC=C1SC1C=CC=C2C=CC=CC2=1
InChiKey:
QTESJCPDPNGOLF-UHFFFAOYSA-N
InChi :
InChI=1S/C18H17NS.ClH/c1-19-13-15-8-3-5-11-17(15)20-18-12-6-9-14-7-2-4-10-16(14)18;/h2-12,19H,13H2,1H3;1H
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
IFN alpha-IFNAR-IN-1 hydrochloride is a nonpeptidic, low-molecular-weight inhibitor of the interaction between IFN-α and IFNAR; inhibit MVA-induced IFN-α responses by BM-pDCs (IC50=2-8 uM). IC50 value: Target: IFN alpha-IFNAR interaction inhibitor IFN alpha-IFNAR-IN-1 specifically inhibits MVA-induced IFN-α responses by BM-pDCs. IFN alpha-IFNAR-IN-1 inhibited the IFN-α responses that were elicited after treatment with CpG2216, stimulation with poly(I:C), and infection with VSV-M2, whereas the total IL-12 production was notably less affected under those conditions. IFN alpha-IFNAR-IN-1 exerts immunosuppressive activity by the direct interaction with IFN-α .|Product information|CAS Number: 2070014-98-9|Molecular Weight: 315.86|Formula: C18H18ClNS|Chemical Name: N-methyl-1-(2-(naphthalen-1-ylthio)phenyl)methanamine hydrochloride|Smiles: Cl.{{SARS-CoV-2 PLpro Protein} MedChemExpress|{SARS-CoV-2 PLpro Protein} Biological Activity|{SARS-CoV-2 PLpro Protein} In stock|{SARS-CoV-2 PLpro Protein} manufacturer|{SARS-CoV-2 PLpro Protein} Autophagy} CNCC1=CC=CC=C1SC1C=CC=C2C=CC=CC2=1|InChiKey: QTESJCPDPNGOLF-UHFFFAOYSA-N|InChi: InChI=1S/C18H17NS.PMID:23543429 ClH/c1-19-13-15-8-3-5-11-17(15)20-18-12-6-9-14-7-2-4-10-16(14)18;/h2-12,19H,13H2,1H3;1H|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 100 mg/mL (316.60 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|