Product Name :
Pexmetinib (ARRY-614)
CAS No.:
945614-12-0
Purity :
> 97%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
CC1=CC=C(C=C1)[N]2N=C(C=C2NC(=O)NCC3=C(OC4=CC5=C(C=C4)[N](CCO)N=C5)C=CC(=C3)F)C(C)(C)C
Product Description :
Pexmetinib (ARRY-614) is a potent, orally bioavailable, dual p38 MAPK/Tie-2 inhibitor with IC50 of 4 nM/18 nM in a HEK-293 cell line.{{Methimazole} MedChemExpress|{Methimazole} Protocol|{Methimazole} Description|{Methimazole} supplier|{Methimazole} Epigenetic Reader Domain} Phase 1.
Formula:
C31H33FN6O3
Molecular Weight :
556.63
Synonyms:
Additional Information:
|CAS No. 945614-12-0 ; |Formula C31H33FN6O3 ; |Molecular Weight 556.{{Prodigiosin} web|{Prodigiosin} Bacterial|{Prodigiosin} Technical Information|{Prodigiosin} Description|{Prodigiosin} custom synthesis|{Prodigiosin} Epigenetics} 63 ; |SMILES CC1=CC=C(C=C1)[N]2N=C(C=C2NC(=O)NCC3=C(OC4=CC5=C(C=C4)[N](CCO)N=C5)C=CC(=C3)F)C(C)(C)C ; |Product Description Pexmetinib (ARRY-614) is a potent, orally bioavailable, dual p38 MAPK/Tie-2 inhibitor with IC50 of 4 nM/18 nM in a HEK-293 cell line.PMID:26895888 Phase 1. ; |Purity > 97% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO