Product Name :
PF-04691502
CAS No.:
1013101-36-4
Purity :
> 99%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
COC1=CC=C(C=N1)C2=CC3=C(C)N=C(N)N=C3N(C4CCC(CC4)OCCO)C2=O
Product Description :
PF-04691502 is an ATP-competitive PI3K(α/β/δ/γ)/mTOR dual inhibitor with Ki of 1.{{p-Coumaric acid} site|{p-Coumaric acid} Anti-infection|{p-Coumaric acid} Purity & Documentation|{p-Coumaric acid} References|{p-Coumaric acid} supplier|{p-Coumaric acid} Autophagy} 8 nM/2.1 nM/1.6 nM/1.9 nM and 16 nM in cell-free assays, little activity against either Vps34, AKT, PDK1, p70S6K, MEK, ERK, p38, or JNK.{{OF-1} medchemexpress|{OF-1} Epigenetics|{OF-1} Biological Activity|{OF-1} Description|{OF-1} custom synthesis|{OF-1} Autophagy} Phase 2.
Formula:
C22H27N5O4
Molecular Weight :
425.PMID:23577779 48
Synonyms:
PF4691502
Additional Information:
|CAS No. 1013101-36-4 ; |Synonyms PF4691502 ; |Formula C22H27N5O4 ; |Molecular Weight 425.48 ; |SMILES COC1=CC=C(C=N1)C2=CC3=C(C)N=C(N)N=C3N(C4CCC(CC4)OCCO)C2=O ; |Target mTOR ; |Product Description PF-04691502 is an ATP-competitive PI3K(α/β/δ/γ)/mTOR dual inhibitor with Ki of 1.8 nM/2.1 nM/1.6 nM/1.9 nM and 16 nM in cell-free assays, little activity against either Vps34, AKT, PDK1, p70S6K, MEK, ERK, p38, or JNK. Phase 2. ; |Purity > 99% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO