Product Name :
PIK-75 HCl
CAS No.:
372196-77-5
Purity :
> 98%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
Cl.CN(/N=C/C1=CN=C2C=CC(=C[N]12)Br)[S](=O)(=O)C3=C(C)C=CC(=C3)[N+]([O-])=O
Product Description :
PIK-75 HCl is a p110α inhibitor with IC50 of 5.8 nM (200-fold more potently than p110β), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM in cell-free assays.
Formula:
C16H15BrClN5O4S
Molecular Weight :
488.74
Synonyms:
Additional Information:
|CAS No. 372196-77-5 ; |Formula C16H15BrClN5O4S ; |Molecular Weight 488.{{Fenebrutinib} web|{Fenebrutinib} Protein Tyrosine Kinase/RTK|{Fenebrutinib} Protocol|{Fenebrutinib} In stock|{Fenebrutinib} supplier|{Fenebrutinib} Cancer} 74 ; |SMILES Cl.{{Celecoxib} site|{Celecoxib} COX|{Celecoxib} Biological Activity|{Celecoxib} Purity|{Celecoxib} custom synthesis|{Celecoxib} Autophagy} CN(/N=C/C1=CN=C2C=CC(=C[N]12)Br)[S](=O)(=O)C3=C(C)C=CC(=C3)[N+]([O-])=O ; |Product Description PIK-75 HCl is a p110α inhibitor with IC50 of 5.PMID:23489613 8 nM (200-fold more potently than p110β), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM in cell-free assays. ; |Purity > 98% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO