Product Name :
PIK-III
CAS No.:
1383716-40-2
Purity :
> 98%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
NC1=NC=C(C(=N1)CC2CC2)C3=CC=NC(=N3)NC4=CC=NC=C4
Product Description :
PIK-III, which is a selective inhibitor of VPS34 enzymatic activity, inhibits autophagy and de novo lipidation of LC3 and leads to the stabilization of autophagy substrates. The IC50 values for VPS34 and PI(3)Kδ are 0.018 μM and 1.{{Guanfacine} medchemexpress|{Guanfacine} Adrenergic Receptor|{Guanfacine} Protocol|{Guanfacine} In Vitro|{Guanfacine} custom synthesis|{Guanfacine} Epigenetics} 2 μM respectively.{{Biperiden} site|{Biperiden} mAChR|{Biperiden} Technical Information|{Biperiden} Data Sheet|{Biperiden} supplier|{Biperiden} Autophagy}
Formula:
C17H17N7
Molecular Weight :
319.PMID:24182988 36
Synonyms:
VPS34-IN2
Additional Information:
|CAS No. 1383716-40-2 ; |Synonyms VPS34-IN2 ; |Formula C17H17N7 ; |Molecular Weight 319.36 ; |SMILES NC1=NC=C(C(=N1)CC2CC2)C3=CC=NC(=N3)NC4=CC=NC=C4 ; |Product Description PIK-III, which is a selective inhibitor of VPS34 enzymatic activity, inhibits autophagy and de novo lipidation of LC3 and leads to the stabilization of autophagy substrates. The IC50 values for VPS34 and PI(3)Kδ are 0.018 μM and 1.2 μM respectively. ; |Purity > 98% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO