Product Name :
Pilaralisib (XL147)
CAS No.:
934526-89-3
Purity :
> 98%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
COC1=CC(=C(Cl)C=C1)NC2=NC3=CC=CC=C3N=C2N[S](=O)(=O)C4=CC=CC(=C4)NC(=O)C(C)(C)N
Product Description :
Pilaralisib (XL147) is a selective and reversible class I PI3K inhibitor for PI3Kα/δ/γ with IC50 of 39 nM/36 nM/23 nM in cell-free assays, less potent to PI3Kβ.{{Orexin 2 Receptor Agonist} web|{Orexin 2 Receptor Agonist} Neuronal Signaling|{Orexin 2 Receptor Agonist} Protocol|{Orexin 2 Receptor Agonist} References|{Orexin 2 Receptor Agonist} manufacturer|{Orexin 2 Receptor Agonist} Autophagy} Phase 1/2.{{Voclosporin} site|{Voclosporin} Phosphatase|{Voclosporin} Purity & Documentation|{Voclosporin} References|{Voclosporin} supplier|{Voclosporin} Cancer}
Formula:
C25H25ClN6O4S
Molecular Weight :
541.02
Synonyms:
Additional Information:
|CAS No. 934526-89-3 ; |Formula C25H25ClN6O4S ; |Molecular Weight 541.02 ; |SMILES COC1=CC(=C(Cl)C=C1)NC2=NC3=CC=CC=C3N=C2N[S](=O)(=O)C4=CC=CC(=C4)NC(=O)C(C)(C)N ; |Target PI3Kβ ; |Product Description Pilaralisib (XL147) is a selective and reversible class I PI3K inhibitor for PI3Kα/δ/γ with IC50 of 39 nM/36 nM/23 nM in cell-free assays, less potent to PI3Kβ.PMID:24360118 Phase 1/2. ; |Purity > 98% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO