Product Name :
Ponatinib (AP24534)
CAS No.:
943319-70-8
Purity :
> 97%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
CN1CCN(CC1)CC2=C(C=C(NC(=O)C3=CC(=C(C)C=C3)C#CC4=CN=C5C=CC=N[N]45)C=C2)C(F)(F)F
Product Description :
Ponatinib (AP24534) is a novel, potent multi-target inhibitor of Abl, PDGFRα, VEGFR2, FGFR1 and Src with IC50 of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM and 5.4 nM in cell-free assays, respectively.
Formula:
C29H27F3N6O
Molecular Weight :
532.56
Synonyms:
Additional Information:
|CAS No.{{AICAR} MedChemExpress|{AICAR} Epigenetics|{AICAR} Protocol|{AICAR} In Vitro|{AICAR} custom synthesis|{AICAR} Epigenetics} 943319-70-8 ; |Formula C29H27F3N6O ; |Molecular Weight 532.{{Fluvastatin} medchemexpress|{Fluvastatin} Autophagy|{Fluvastatin} Biological Activity|{Fluvastatin} Formula|{Fluvastatin} custom synthesis|{Fluvastatin} Cancer} 56 ; |SMILES CN1CCN(CC1)CC2=C(C=C(NC(=O)C3=CC(=C(C)C=C3)C#CC4=CN=C5C=CC=N[N]45)C=C2)C(F)(F)F ; |Product Description Ponatinib (AP24534) is a novel, potent multi-target inhibitor of Abl, PDGFRα, VEGFR2, FGFR1 and Src with IC50 of 0.PMID:24982871 37 nM, 1.1 nM, 1.5 nM, 2.2 nM and 5.4 nM in cell-free assays, respectively. ; |Purity > 97% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO