Product Name :
PTP1B/AKR1B1-IN-2
CAS No.:
Purity :
Shipping:
Room temperature in the continental U.S. Other areas may vary.
Storage :
Please store the product under the recommended conditions in the Certificate of Analysis.
SMILES:
O=C(CCN1C(/C(SC1=S)=C/C2=CC=CC(OCCCCC3=CC=CC=C3)=C2)=O)O
Product Description :
PTP1B/AKR1B1-IN-2 (Compound 7f) is a dual PTP1B/AKR1B1 inhibitor (IC50s: 3.2 and 2.{{Telisotuzumab} medchemexpress|{Telisotuzumab} Purity & Documentation|{Telisotuzumab} References|{Telisotuzumab} custom synthesis|{Telisotuzumab} Epigenetic Reader Domain} 1 μM, Kis: 4.0 and 0.{{Irinotecan hydrochloride} medchemexpress|{Irinotecan hydrochloride} Topoisomerase|{Irinotecan hydrochloride} Biological Activity|{Irinotecan hydrochloride} References|{Irinotecan hydrochloride} custom synthesis|{Irinotecan hydrochloride} Cancer} 9μM). PTP1B/AKR1B1-IN-2 is an insulin-mimetic agent.PMID:25269910 PTP1B/AKR1B1-IN-2 improves glucose uptake in murine C2C12 myoblasts. PTP1B/AKR1B1-IN-2 can be used for research of Type 2 diabetes mellitus (T2DM).
Formula:
C23H23NO4S2
Molecular Weight :
441.56
Synonyms:
Additional Information:
|Formula C23H23NO4S2 ; |Molecular Weight 441.56 ; |SMILES O=C(CCN1C(/C(SC1=S)=C/C2=CC=CC(OCCCCC3=CC=CC=C3)=C2)=O)O ; |Target Phosphatase, Aldose Reductase ; |Product Description PTP1B/AKR1B1-IN-2 (Compound 7f) is a dual PTP1B/AKR1B1 inhibitor (IC50s: 3.2 and 2.1 μM, Kis: 4.0 and 0.9μM). PTP1B/AKR1B1-IN-2 is an insulin-mimetic agent. PTP1B/AKR1B1-IN-2 improves glucose uptake in murine C2C12 myoblasts. PTP1B/AKR1B1-IN-2 can be used for research of Type 2 diabetes mellitus (T2DM). ; |Shipping Room temperature in the continental U.S. Other areas may vary. ; |Storage Please store the product under the recommended conditions in the Certificate of Analysis.