Product Name :
Purmorphamine
CAS No.:
483367-10-8
Purity :
> 98%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
C1CCC(CC1)[N]2C=NC3=C2N=C(OC4=C5C=CC=CC5=CC=C4)N=C3NC6=CC=C(C=C6)N7CCOCC7
Product Description :
Purmorphamine, which directly binds and activates Smoothened, blocks BODIPY-cyclopamine binding to Smo with IC50 of ~ 1.{{Simtuzumab} site|{Simtuzumab} Neuronal Signaling|{Simtuzumab} Protocol|{Simtuzumab} Purity|{Simtuzumab} custom synthesis|{Simtuzumab} Cancer} 5 μM in HEK293T cell and also is an inducer of osteoblast differentiation with EC50 of 1 μM.
Formula:
C31H32N6O2
Molecular Weight :
520.62
Synonyms:
Additional Information:
|CAS No. 483367-10-8 ; |Formula C31H32N6O2 ; |Molecular Weight 520.62 ; |SMILES C1CCC(CC1)[N]2C=NC3=C2N=C(OC4=C5C=CC=CC5=CC=C4)N=C3NC6=CC=C(C=C6)N7CCOCC7 ; |Product Description Purmorphamine, which directly binds and activates Smoothened, blocks BODIPY-cyclopamine binding to Smo with IC50 of ~ 1.{{Didox} medchemexpress|{Didox} Cell Cycle/DNA Damage|{Didox} Purity & Documentation|{Didox} Data Sheet|{Didox} manufacturer|{Didox} Autophagy} 5 μM in HEK293T cell and also is an inducer of osteoblast differentiation with EC50 of 1 μM.PMID:24487575 ; |Purity > 98% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO