Product Name :
Alvespimycin HCl
CAS No.:
467214-21-7
Purity :
> 95%
Shipping:
Shipped at room temperature.
Storage :
Store at or below –20 °C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
SMILES:
Product Description :
Alvespimycin HCl, also known as 17-DMAG, is a potent, water-soluble HSP90 inhibitor. Alvespimycin has diverse anti-tumor actions and has potential in treating a number of different types of cancers, including ovarian, prostate, melatnoma, non-small-cell lung cancer, and several leukemias (chronic lymphocytic, acute myeloid). This compound also suppresses inflammation by interfering with signaling through the NF-κB pathway.
Formula:
C32H48N4O8 • HCl
Molecular Weight :
653.{{Dacomitinib} MedChemExpress|{Dacomitinib} Protein Tyrosine Kinase/RTK|{Dacomitinib} Protocol|{Dacomitinib} In Vivo|{Dacomitinib} custom synthesis|{Dacomitinib} Cancer} 2
Synonyms:
17-DMAG, KOS-1022, NSC707545, 17-demethoxy-17-[[2-(dimethylamino)ethyl]amino]-geldanamycin
Additional Information:
|CAS No.{{Fluphenazine} MedChemExpress|{Fluphenazine} SARS-CoV|{Fluphenazine} Biological Activity|{Fluphenazine} Data Sheet|{Fluphenazine} supplier|{Fluphenazine} Autophagy} 467214-21-7 ; |Synonyms 17-DMAG, KOS-1022, NSC707545, 17-demethoxy-17-[[2-(dimethylamino)ethyl]amino]-geldanamycin ; |Formula C32H48N4O8 • HCl ; |Molecular Weight 653.PMID:27102143 2 ; |Target HSP90 ; |Product Description Alvespimycin HCl, also known as 17-DMAG, is a potent, water-soluble HSP90 inhibitor. Alvespimycin has diverse anti-tumor actions and has potential in treating a number of different types of cancers, including ovarian, prostate, melatnoma, non-small-cell lung cancer, and several leukemias (chronic lymphocytic, acute myeloid). This compound also suppresses inflammation by interfering with signaling through the NF-κB pathway. ; |Format Solid ; |Purity > 95% ; |Shipping Shipped at room temperature. ; |Storage Store at or below –20 °C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day. ; |Solubility Overview Soluble in DMSO (100 mM). Solubility in water is less than 1 mg/mL (1 mM).