Product Name :
R788 (Fostamatinib) Disodium
CAS No.:
1025687-58-4
Purity :
> 99%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
[Na+].[Na+].COC1=C(OC)C(=CC(=C1)NC2=NC=C(F)C(=N2)NC3=CC=C4OC(C)(C)C(=O)N(CO[P]([O-])([O-])=O)C4=N3)OC
Product Description :
R788 (Fostamatinib) disodium, a prodrug of the active metabolite R406, is a Syk inhibitor with IC50 of 41 nM in a cell-free assay, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3.
Formula:
C23H24FN6Na2O9P
Molecular Weight :
624.42
Synonyms:
Tamatinib Fosdium
Additional Information:
|CAS No.{{Paxalisib} web|{Paxalisib} PI3K|{Paxalisib} Purity & Documentation|{Paxalisib} In Vitro|{Paxalisib} custom synthesis|{Paxalisib} Epigenetic Reader Domain} 1025687-58-4 ; |Synonyms Tamatinib Fosdium ; |Formula C23H24FN6Na2O9P ; |Molecular Weight 624.{{Boceprevir} web|{Boceprevir} Metabolic Enzyme/Protease|{Boceprevir} Technical Information|{Boceprevir} In Vivo|{Boceprevir} custom synthesis|{Boceprevir} Cancer} 42 ; |SMILES [Na+].PMID:23557924 [Na+].COC1=C(OC)C(=CC(=C1)NC2=NC=C(F)C(=N2)NC3=CC=C4OC(C)(C)C(=O)N(CO[P]([O-])([O-])=O)C4=N3)OC ; |Product Description R788 (Fostamatinib) disodium, a prodrug of the active metabolite R406, is a Syk inhibitor with IC50 of 41 nM in a cell-free assay, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. ; |Format Solid ; |Purity > 99% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO