Product Name :
Regorafenib (BAY 73-4506)
CAS No.:
755037-03-7
Purity :
> 99%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
CNC(=O)C1=CC(=CC=N1)OC2=CC(=C(NC(=O)NC3=CC=C(Cl)C(=C3)C(F)(F)F)C=C2)F
Product Description :
Regorafenib (BAY 73-4506) is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit, RET and Raf-1 with IC50 of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM in cell-free assays, respectively.
Formula:
C21H15ClF4N4O3
Molecular Weight :
482.{{Capmatinib} web|{Capmatinib} Protein Tyrosine Kinase/RTK|{Capmatinib} Protocol|{Capmatinib} In stock|{Capmatinib} custom synthesis|{Capmatinib} Autophagy} 82
Synonyms:
Fluoro-Sorafenib
Additional Information:
|CAS No.{{Pegaptanib} medchemexpress|{Pegaptanib} Protein Tyrosine Kinase/RTK|{Pegaptanib} Technical Information|{Pegaptanib} In stock|{Pegaptanib} custom synthesis|{Pegaptanib} Autophagy} 755037-03-7 ; |Synonyms Fluoro-Sorafenib ; |Formula C21H15ClF4N4O3 ; |Molecular Weight 482.PMID:32180353 82 ; |SMILES CNC(=O)C1=CC(=CC=N1)OC2=CC(=C(NC(=O)NC3=CC=C(Cl)C(=C3)C(F)(F)F)C=C2)F ; |Target VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit, RET and Raf-1 ; |Product Description Regorafenib (BAY 73-4506) is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit, RET and Raf-1 with IC50 of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM in cell-free assays, respectively. ; |Purity > 99% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO