Product Name :
Ridaforolimus (Deforolimus, MK-8669)
CAS No.:
572924-54-0
Purity :
> 98%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
COC1CC(CCC1O[P](C)(C)=O)CC(C)C2CC(=O)C(C)\C=C(C)\C(O)C(OC)C(=O)C(C)CC(C)/C=C/C=C/C=C(C)/C(CC3CCC(C)C(O)(O3)C(=O)C(=O)N4CCCCC4C(=O)O2)OC
Product Description :
Ridaforolimus (Deforolimus, MK-8669) is a selective mTOR inhibitor with IC50 of 0.2 nM in HT-1080 cell line while not classified as a prodrug, mTOR inhibition and FKBP12 binding is similar to rapamycin. Phase 3.
Formula:
C53H84NO14P
Molecular Weight :
990.21
Synonyms:
AP23573
Additional Information:
|CAS No.{{Biotin} medchemexpress|{Biotin} Metabolic Enzyme/Protease|{Biotin} Technical Information|{Biotin} Description|{Biotin} custom synthesis|{Biotin} Cancer} 572924-54-0 ; |Synonyms AP23573 ; |Formula C53H84NO14P ; |Molecular Weight 990.{{Osimertinib} medchemexpress|{Osimertinib} JAK/STAT Signaling|{Osimertinib} Purity & Documentation|{Osimertinib} Data Sheet|{Osimertinib} manufacturer|{Osimertinib} Autophagy} 21 ; |SMILES COC1CC(CCC1O[P](C)(C)=O)CC(C)C2CC(=O)C(C)\C=C(C)\C(O)C(OC)C(=O)C(C)CC(C)/C=C/C=C/C=C(C)/C(CC3CCC(C)C(O)(O3)C(=O)C(=O)N4CCCCC4C(=O)O2)OC ; |Target mTOR ; |Product Description Ridaforolimus (Deforolimus, MK-8669) is a selective mTOR inhibitor with IC50 of 0.PMID:34235739 2 nM in HT-1080 cell line while not classified as a prodrug, mTOR inhibition and FKBP12 binding is similar to rapamycin. Phase 3. ; |Purity > 98% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO