Product Name :
Ruxolitinib (INCB018424)
CAS No.:
941678-49-5
Purity :
> 99%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
N#CCC(C1CCCC1)[N]2C=C(C=N2)C3=NC=NC4=C3C=C[NH]4
Product Description :
Ruxolitinib (INCB018424) is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM in cell-free assays, >130-fold selectivity for JAK1/2 versus JAK3.
Formula:
C17H18N6
Molecular Weight :
306.37
Synonyms:
Additional Information:
|CAS No. 941678-49-5 ; |Formula C17H18N6 ; |Molecular Weight 306.37 ; |SMILES N#CCC(C1CCCC1)[N]2C=C(C=N2)C3=NC=NC4=C3C=C[NH]4 ; |Target JAK1/2 ; |Product Description Ruxolitinib (INCB018424) is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.{{Monomethyl} site|{Monomethyl} GPCR/G Protein|{Monomethyl} Purity & Documentation|{Monomethyl} References|{Monomethyl} manufacturer|{Monomethyl} Epigenetics} 3 nM/2.{{Lacidipine} medchemexpress|{Lacidipine} Caspase|{Lacidipine} Technical Information|{Lacidipine} In stock|{Lacidipine} supplier|{Lacidipine} Cancer} 8 nM in cell-free assays, >130-fold selectivity for JAK1/2 versus JAK3.PMID:24182988 ; |Purity > 99% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO