Product Name :
S-Ruxolitinib (INCB018424)
CAS No.:
941685-37-6
Purity :
> 99%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
N#CCC(C1CCCC1)[N]2C=C(C=N2)C3=NC=NC4=C3C=C[NH]4
Product Description :
S-Ruxolitinib is the chirality of INCB018424, which is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3. Phase 3.
Formula:
C17H18N6
Molecular Weight :
306.37
Synonyms:
Additional Information:
|CAS No. 941685-37-6 ; |Formula C17H18N6 ; |Molecular Weight 306.37 ; |SMILES N#CCC(C1CCCC1)[N]2C=C(C=N2)C3=NC=NC4=C3C=C[NH]4 ; |Product Description S-Ruxolitinib is the chirality of INCB018424, which is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.{{CNTF Protein, Human} medchemexpress|{CNTF Protein, Human} Biological Activity|{CNTF Protein, Human} Data Sheet|{CNTF Protein, Human} manufacturer|{CNTF Protein, Human} Autophagy} 3 nM/2.{{Ampicillin} web|{Ampicillin} Bacterial|{Ampicillin} Technical Information|{Ampicillin} In stock|{Ampicillin} manufacturer|{Ampicillin} Autophagy} 8 nM, >130-fold selectivity for JAK1/2 versus JAK3.PMID:23916866 Phase 3. ; |Purity > 99% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO