Product Name :
AMG-319
CAS No.:
1608125-21-8
Purity :
> 98%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
CC(NC1=C2N=C[NH]C2=NC=N1)C3=C(N=C4C=C(F)C=CC4=C3)C5=CC=CC=N5
Product Description :
AMG319 is a potent and selective PI3Kδ inhibitor with IC50 of 18 nM, >47-fold selectivity over other PI3Ks. Phase 2.
Formula:
C21H16FN7
Molecular Weight :
385.4
Synonyms:
Additional Information:
|CAS No. 1608125-21-8 ; |Formula C21H16FN7 ; |Molecular Weight 385.4 ; |SMILES CC(NC1=C2N=C[NH]C2=NC=N1)C3=C(N=C4C=C(F)C=CC4=C3)C5=CC=CC=N5 ; |Target PI3Kδ ; |Product Description AMG319 is a potent and selective PI3Kδ inhibitor with IC50 of 18 nM, >47-fold selectivity over other PI3Ks.{{WS-12} site|{WS-12} Neuronal Signaling|{WS-12} Biological Activity|{WS-12} In Vivo|{WS-12} supplier|{WS-12} Autophagy} Phase 2.{{Trilaciclib} site|{Trilaciclib} CDK|{Trilaciclib} Purity & Documentation|{Trilaciclib} Purity|{Trilaciclib} supplier|{Trilaciclib} Autophagy} ; |Purity > 98% ; |Shipping Shipped on dry ice.PMID:23991096 ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO