Product Name :
Quinpirole Hydrochloride
Description:
Quinpirole Hydrochloride ((-)-LY 171555) is a high-affinity agonist of dopamine D2/D3 receptor.
CAS:
85798-08-9
Molecular Weight:
255.79
Formula:
C13H22ClN3
Chemical Name:
(8aR)-5-propyl-1H,4H,4aH,5H,6H,7H,8H,8aH,9H-pyrido[2,3-f]indazole hydrochloride
Smiles :
Cl.CCCN1CCC[C@@H]2CC3NN=CC=3CC12
InChiKey:
HJHVRVJTYPKTHX-HXOUFFEYSA-N
InChi :
InChI=1S/C13H21N3.ClH/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12;/h9-10,13H,2-8H2,1H3,(H,14,15);1H/t10-,13?;/m1./s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Lemzoparlimab} medchemexpress|{Lemzoparlimab} Immunology/Inflammation|{Lemzoparlimab} TGF-beta/Smad|{Lemzoparlimab} Protocol|{Lemzoparlimab} In Vivo|{Lemzoparlimab} manufacturer}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Quinpirole Hydrochloride ((-)-LY 171555) is a high-affinity agonist of dopamine D2/D3 receptor.|Product information|CAS Number: 85798-08-9|Molecular Weight: 255.79|Formula: C13H22ClN3|Chemical Name: (8aR)-5-propyl-1H,4H,4aH,5H,6H,7H,8H,8aH,9H-pyrido[2,3-f]indazole hydrochloride|Smiles: Cl.CCCN1CCC[C@@H]2CC3NN=CC=3CC12|InChiKey: HJHVRVJTYPKTHX-HXOUFFEYSA-N|InChi: InChI=1S/C13H21N3.ClH/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12;/h9-10,13H,2-8H2,1H3,(H,14,15);1H/t10-,13?;/m1./s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 27.78 mg/mL (108.60 mM; Need ultrasonic). H2O : 50 mg/mL (195.47 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|DA content is left brain biased across groups, and although this asymmetry appears greater in saline controls than all drug-treated groups, there is not a significant interaction between Side and Group.{{Estrone} web|{Estrone} Endogenous Metabolite|{Estrone} Technical Information|{Estrone} In Vitro|{Estrone} manufacturer|{Estrone} Autophagy} When each side is considered separately it can be seen that in the left brain structure, DA levels progressively decrease with chronic quinpirole treatment, with the QQ rats differing significantly from saline controls.PMID:23672196 In contrast, right cortical DA levels are only altered significantly (increased) by acute Quinpirole. It can be found that DOPAC levels are also left brain biased across groups. However, no significant Group or interaction effects are found. Rats receiving acute Quinpirole show a selective increase in DA content and decrease in turnover ratio, relative to either saline controls or the QS group. Sensitized (QQ) rats however, have elevated DOPAC levels in comparison to the acute quinpirole group. In striatum as well, all three measures of DA function differed significantly across groups (DA, F3,33=6.27, P=0.0020; DOPAC, F3,33=7.98, P=0.0004; turnover ratio, F3,33=16.85, PProducts are for research use only. Not for human use.|