Product Name :
SAR131675
CAS No.:
1433953-83-3
Purity :
> 99%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
CCN1C(=C(C(=O)NC)C(=O)C2=CC=C(N=C12)C#CC(C)(O)COC)N
Product Description :
SAR131675 is a VEGFR3 inhibitor with IC50/Ki of 23 nM/12 nM in cell-free assays, about 50- and 10-fold more selective for VEGFR3 than VEGFR1/2, little activity against Akt1, CDKs, PLK1, EGFR, IGF-1R, c-Met, Flt2 etc.
Formula:
C18H22N4O4
Molecular Weight :
358.39
Synonyms:
Additional Information:
|CAS No. 1433953-83-3 ; |Formula C18H22N4O4 ; |Molecular Weight 358.{{Tebentafusp} medchemexpress|{Tebentafusp} Immunology/Inflammation|{Tebentafusp} Protocol|{Tebentafusp} In stock|{Tebentafusp} custom synthesis|{Tebentafusp} Epigenetic Reader Domain} 39 ; |SMILES CCN1C(=C(C(=O)NC)C(=O)C2=CC=C(N=C12)C#CC(C)(O)COC)N ; |Target VEGFR3 ; |Product Description SAR131675 is a VEGFR3 inhibitor with IC50/Ki of 23 nM/12 nM in cell-free assays, about 50- and 10-fold more selective for VEGFR3 than VEGFR1/2, little activity against Akt1, CDKs, PLK1, EGFR, IGF-1R, c-Met, Flt2 etc.{{Phenylbutyrate} MedChemExpress|{Phenylbutyrate} Epigenetics|{Phenylbutyrate} Biological Activity|{Phenylbutyrate} Purity|{Phenylbutyrate} custom synthesis|{Phenylbutyrate} Autophagy} ; |Purity > 99% ; |Shipping Shipped on dry ice.PMID:23415682 ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO