Product Name :
SB-203580
CAS No.:
152121-47-6
Purity :
> 99%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
C[S](=O)C1=CC=C(C=C1)C2=NC(=C([NH]2)C3=CC=NC=C3)C4=CC=C(F)C=C4
Product Description :
SB203580 is a p38 MAPK inhibitor with IC50 of 0.{{Zibotentan} MedChemExpress|{Zibotentan} Apoptosis|{Zibotentan} Purity & Documentation|{Zibotentan} Purity|{Zibotentan} custom synthesis|{Zibotentan} Epigenetic Reader Domain} 3-0.5 μM in THP-1 cells, 10-fold less sensitive to SAPK3(106T) and SAPK4(106T) and blocks PKB phosphorylation with IC50 of 3-5 μM.
Formula:
C21H16FN3OS
Molecular Weight :
377.43
Synonyms:
RWJ 64809, PB 203580
Additional Information:
|CAS No. 152121-47-6 ; |Synonyms RWJ 64809, PB 203580 ; |Formula C21H16FN3OS ; |Molecular Weight 377.{{Glycitin} medchemexpress|{Glycitin} Anti-infection|{Glycitin} Purity & Documentation|{Glycitin} Formula|{Glycitin} manufacturer|{Glycitin} Epigenetic Reader Domain} 43 ; |SMILES C[S](=O)C1=CC=C(C=C1)C2=NC(=C([NH]2)C3=CC=NC=C3)C4=CC=C(F)C=C4 ; |Product Description SB203580 is a p38 MAPK inhibitor with IC50 of 0.PMID:23833812 3-0.5 μM in THP-1 cells, 10-fold less sensitive to SAPK3(106T) and SAPK4(106T) and blocks PKB phosphorylation with IC50 of 3-5 μM. ; |Purity > 99% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO