Product Name :
Mazdutide TFA
CAS No.:
Purity :
Shipping:
Room temperature in the continental U.S. Other areas may vary.
Storage :
Please store the product under the recommended conditions in the Certificate of Analysis.
SMILES:
Product Description :
Mazdutide (IBI-362; LY-3305677) TFA is a long-acting synthetic oxyntomodulin analog. Mazdutide is also a co-agonist of glucagon-like peptide (GLP-1R) and glucagon receptor (GCGR). Mazdutide TFA binds human and mouse GCGR (Ki: 17.7 nM and 15.9 nM, respectively) and GLP-1R (Ki: 28.6 nM and 25.1 nM, respectively) and stimulates insulin secretion from mouse islets (EC50: 5.2 nM). Mazdutide TFA is used in studies of obesity and type 2 diabetes (T2D).
Formula:
C210H322N46O67.xC2HF3O2
Molecular Weight :
4563.06 (free base)
Synonyms:
IBI-362 TFA; LY-3305677 TFA; OXM-3 TFA
Additional Information:
|Synonyms IBI-362 TFA; LY-3305677 TFA; OXM-3 TFA ; |Formula C210H322N46O67.Artemisinin xC2HF3O2 ; |Molecular Weight 4563.Anti-Mouse CD8 beta Antibody 06 (free base) ; |Target GCGR, GLP Receptor ; |Product Description Mazdutide (IBI-362; LY-3305677) TFA is a long-acting synthetic oxyntomodulin analog. Mazdutide is also a co-agonist of glucagon-like peptide (GLP-1R) and glucagon receptor (GCGR).PMID:25269910 Mazdutide TFA binds human and mouse GCGR (Ki: 17.7 nM and 15.9 nM, respectively) and GLP-1R (Ki: 28.6 nM and 25.1 nM, respectively) and stimulates insulin secretion from mouse islets (EC50: 5.2 nM). Mazdutide TFA is used in studies of obesity and type 2 diabetes (T2D). ; |Shipping Room temperature in the continental U.S. Other areas may vary. ; |Storage Please store the product under the recommended conditions in the Certificate of Analysis.