Product Name :
Pamapimod (R-1503, Ro4402257)
CAS No.:
449811-01-2
Purity :
> 98%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
CN1C(=O)C(=CC2=CN=C(NC(CCO)CCO)N=C12)OC3=C(F)C=C(F)C=C3
Product Description :
Pamapimod (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase.{{Nitisinone} MedChemExpress|{Nitisinone} Metabolic Enzyme/Protease|{Nitisinone} Purity & Documentation|{Nitisinone} Data Sheet|{Nitisinone} manufacturer|{Nitisinone} Epigenetic Reader Domain} It inhibits p38α and p38β enzymatic activity with IC50 values of 0.{{CPDA} MedChemExpress|{CPDA} Metabolic Enzyme/Protease|{CPDA} Protocol|{CPDA} Purity|{CPDA} custom synthesis|{CPDA} Epigenetic Reader Domain} 014±0.002 and 0.48± 0.04 microM, respectively with no activity against p38delta or p38gamma isoforms.
Formula:
C19H20F2N4O4
Molecular Weight :
406.38
Synonyms:
Additional Information:
|CAS No. 449811-01-2 ; |Formula C19H20F2N4O4 ; |Molecular Weight 406.38 ; |SMILES CN1C(=O)C(=CC2=CN=C(NC(CCO)CCO)N=C12)OC3=C(F)C=C(F)C=C3 ; |Product Description Pamapimod (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase.PMID:24220671 It inhibits p38α and p38β enzymatic activity with IC50 values of 0.014±0.002 and 0.48± 0.04 microM, respectively with no activity against p38delta or p38gamma isoforms. ; |Purity > 98% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO