Product Name :
PF-4708671
CAS No.:
1255517-76-0
Purity :
> 98%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
CCC1=CN=CN=C1N2CCN(CC2)CC3=NC4=C([NH]3)C=CC(=C4)C(F)(F)F
Product Description :
PF-4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) with Ki/IC50 of 20 nM/160 nM in cell-free assays, 400-fold greater selectivity for S6K1 than S6K2, and 4- and >20-fold selectivity for S6K1 than MSK1 and RSK1/2, respectively. First S6K1-specific inhibitor to be reported.
Formula:
C19H21F3N6
Molecular Weight :
390.{{Vilobelimab} web|{Vilobelimab} SARS-CoV|{Vilobelimab} Technical Information|{Vilobelimab} In Vivo|{Vilobelimab} supplier|{Vilobelimab} Epigenetics} 41
Synonyms:
Additional Information:
|CAS No.{{Bupivacaine} site|{Bupivacaine} Calcium Channel|{Bupivacaine} Technical Information|{Bupivacaine} In Vivo|{Bupivacaine} custom synthesis|{Bupivacaine} Cancer} 1255517-76-0 ; |Formula C19H21F3N6 ; |Molecular Weight 390.PMID:24733396 41 ; |SMILES CCC1=CN=CN=C1N2CCN(CC2)CC3=NC4=C([NH]3)C=CC(=C4)C(F)(F)F ; |Product Description PF-4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) with Ki/IC50 of 20 nM/160 nM in cell-free assays, 400-fold greater selectivity for S6K1 than S6K2, and 4- and >20-fold selectivity for S6K1 than MSK1 and RSK1/2, respectively. First S6K1-specific inhibitor to be reported. ; |Purity > 98% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO