Product Name :
Piperlongumine
CAS No.:
20069-09-4
Purity :
> 98%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
COC1=CC(=CC(=C1OC)OC)/C=C/C(=O)N2CCC=CC2=O
Product Description :
Piperlongumine, a natural alkaloid from Piper longum L.{{Xevinapant} MedChemExpress|{Xevinapant} IAP|{Xevinapant} Technical Information|{Xevinapant} In Vitro|{Xevinapant} supplier|{Xevinapant} Epigenetic Reader Domain} , increases the level of reactive oxygen species (ROS) and selectively kills cancer cells. It is a direct TrxR1 inhibitor with suppressive activity against gastric cancer and a novel inhibitor of CRM1 also an inhibitor of PI3K/Akt/mTOR in human breast cancer cells.
Formula:
C17H19NO5
Molecular Weight :
317.34
Synonyms:
PPLGM, Piplartine
Additional Information:
|CAS No.{{D-Glucose} site|{D-Glucose} Endogenous Metabolite|{D-Glucose} Biological Activity|{D-Glucose} Description|{D-Glucose} manufacturer|{D-Glucose} Epigenetics} 20069-09-4 ; |Synonyms PPLGM, Piplartine ; |Formula C17H19NO5 ; |Molecular Weight 317.PMID:24631563 34 ; |SMILES COC1=CC(=CC(=C1OC)OC)/C=C/C(=O)N2CCC=CC2=O ; |Target PI3K/Akt/mTOR ; |Product Description Piperlongumine, a natural alkaloid from Piper longum L., increases the level of reactive oxygen species (ROS) and selectively kills cancer cells. It is a direct TrxR1 inhibitor with suppressive activity against gastric cancer and a novel inhibitor of CRM1 also an inhibitor of PI3K/Akt/mTOR in human breast cancer cells. ; |Purity > 98% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO