Product Name :
PLX-4720
CAS No.:
918505-84-7
Purity :
> 99%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
CCC[S](=O)(=O)NC1=CC=C(F)C(=C1F)C(=O)C2=C[NH]C3=NC=C(Cl)C=C23
Product Description :
PLX4720 is a potent and selective inhibitor of B-RafV600E with IC50 of 13 nM in a cell-free assay, equally potent to c-Raf-1(Y340D and Y341D mutations), 10-fold selectivity for B-RafV600E than wild-type B-Raf.
Formula:
C17H14ClF2N3O3S
Molecular Weight :
413.83
Synonyms:
Additional Information:
|CAS No.{{Topiramate} medchemexpress|{Topiramate} Carbonic Anhydrase|{Topiramate} Purity & Documentation|{Topiramate} Description|{Topiramate} manufacturer|{Topiramate} Autophagy} 918505-84-7 ; |Formula C17H14ClF2N3O3S ; |Molecular Weight 413.{{CF53} medchemexpress|{CF53} Epigenetics|{CF53} Technical Information|{CF53} In stock|{CF53} manufacturer|{CF53} Epigenetics} 83 ; |SMILES CCC[S](=O)(=O)NC1=CC=C(F)C(=C1F)C(=O)C2=C[NH]C3=NC=C(Cl)C=C23 ; |Target c-Raf-1 ; |Product Description PLX4720 is a potent and selective inhibitor of B-RafV600E with IC50 of 13 nM in a cell-free assay, equally potent to c-Raf-1(Y340D and Y341D mutations), 10-fold selectivity for B-RafV600E than wild-type B-Raf.PMID:24578169 ; |Purity > 99% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO