Product Name :
PLX7904
CAS No.:
1393465-84-3
Purity :
> 99%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
CCN(C)[S](=O)(=O)NC1=CC=C(F)C(=C1F)C(=O)C2=C[NH]C3=NC=C(C=C23)C4=CN=C(N=C4)C5CC5
Product Description :
PLX7904, also known as PB04, is a potent and selective paradox-breaker RAF inhibitor. It is able to efficiently inhibit activation of ERK1/2 in mutant BRAF melanoma cells but does not hyperactivate ERK1/2 in mutant RAS-expressing cells.
Formula:
C24H22F2N6O3S
Molecular Weight :
512.53
Synonyms:
PB04
Additional Information:
|CAS No.{{DCVC} medchemexpress|{DCVC} TNF Receptor|{DCVC} Protocol|{DCVC} Description|{DCVC} supplier|{DCVC} Cancer} 1393465-84-3 ; |Synonyms PB04 ; |Formula C24H22F2N6O3S ; |Molecular Weight 512.{{Cibinetide} MedChemExpress|{Cibinetide} Purity & Documentation|{Cibinetide} Description|{Cibinetide} custom synthesis|{Cibinetide} Autophagy} 53 ; |SMILES CCN(C)[S](=O)(=O)NC1=CC=C(F)C(=C1F)C(=O)C2=C[NH]C3=NC=C(C=C23)C4=CN=C(N=C4)C5CC5 ; |Product Description PLX7904, also known as PB04, is a potent and selective paradox-breaker RAF inhibitor.PMID:23865629 It is able to efficiently inhibit activation of ERK1/2 in mutant BRAF melanoma cells but does not hyperactivate ERK1/2 in mutant RAS-expressing cells. ; |Purity > 99% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO