Product Name :
Alvelestat (AZD9668)
CAS No.:
848141-11-7
Purity :
> 99%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
C[N]1N=CC=C1C2=CN(C(=O)C(=C2)C(=O)NCC3=NC=C(C=C3)[S](C)(=O)=O)C4=CC=CC(=C4)C(F)(F)F
Product Description :
Alvelestat (AZD9668) is an oral, highly selective inhibitor of neutrophil elastase (NE) with IC50 and Ki of 12 nM and 9.4 nM, at least 600-fold more selective over other serine proteases.
Formula:
C24H20F3N5O4S
Molecular Weight :
545.53
Synonyms:
Avelestat
Additional Information:
|CAS No. 848141-11-7 ; |Synonyms Avelestat ; |Formula C24H20F3N5O4S ; |Molecular Weight 545.53 ; |SMILES C[N]1N=CC=C1C2=CN(C(=O)C(=C2)C(=O)NCC3=NC=C(C=C3)[S](C)(=O)=O)C4=CC=CC(=C4)C(F)(F)F ; |Product Description Alvelestat (AZD9668) is an oral, highly selective inhibitor of neutrophil elastase (NE) with IC50 and Ki of 12 nM and 9.{{G36} MedChemExpress|{G36} Estrogen Receptor/ERR|{G36} Biological Activity|{G36} Purity|{G36} custom synthesis|{G36} Autophagy} 4 nM, at least 600-fold more selective over other serine proteases.{{Congo Red} MedChemExpress|{Congo Red} {Fluorescent Dye}|{Congo Red} Technical Information|{Congo Red} In Vivo|{Congo Red} manufacturer|{Congo Red} Epigenetics} ; |Format Solid ; |Purity > 99% ; |Shipping Shipped on dry ice.PMID:22664133 ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO