Product Name :
AMG-221
CAS No.:
1095565-81-3
Purity :
Shipping:
Room temperature in the continental U.S. Other areas may vary.
Storage :
Please store the product under the recommended conditions in the Certificate of Analysis.
SMILES:
O=C1N=C(N[C@@H]2[C@@](C3)([H])CC[C@@]3([H])C2)S[C@@]1(C)C(C)C
Product Description :
AMG-221 is an inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) with a Ki of 12.{{Etokimab} web|{Etokimab} Interleukin Related|{Etokimab} Purity & Documentation|{Etokimab} References|{Etokimab} supplier|{Etokimab} Cancer} 8 nM in vitro biochemical scintillation proximity assay (SPA) and an IC50 of 10.1 nM in cell-based assays. AMG-221 can be used for the research of type 2 diabetes.
Formula:
C14H22N2OS
Molecular Weight :
266.40
Synonyms:
Additional Information:
|CAS No. 1095565-81-3 ; |Formula C14H22N2OS ; |Molecular Weight 266.40 ; |SMILES O=C1N=C(N[C@@H]2[C@@](C3)([H])CC[C@@]3([H])C2)S[C@@]1(C)C(C)C ; |Target 11β-HSD ; |Product Description AMG-221 is an inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) with a Ki of 12.{{Dantrolene} medchemexpress|{Dantrolene} Membrane Transporter/Ion Channel|{Dantrolene} Biological Activity|{Dantrolene} In Vitro|{Dantrolene} manufacturer|{Dantrolene} Cancer} 8 nM in vitro biochemical scintillation proximity assay (SPA) and an IC50 of 10.PMID:23773119 1 nM in cell-based assays. AMG-221 can be used for the research of type 2 diabetes. ; |Shipping Room temperature in the continental U.S. Other areas may vary. ; |Storage Please store the product under the recommended conditions in the Certificate of Analysis.