Product Name :
Sapanisertib (INK 128, MLN0128)
CAS No.:
1224844-38-5
Purity :
> 97%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
CC(C)[N]1N=C(C2=CC3=C(OC(=N3)N)C=C2)C4=C(N)N=CN=C14
Product Description :
Sapanisertib (INK 128, MLN0128) is a potent and selective mTOR inhibitor with IC50 of 1 nM in cell-free assays >200-fold less potent to class I PI3K isoforms, superior in blocking mTORC1/2 and sensitive to pro-invasion genes (vs Rapamycin).{{Trifluridine} medchemexpress|{Trifluridine} DNA/RNA Synthesis|{Trifluridine} Protocol|{Trifluridine} In Vivo|{Trifluridine} custom synthesis|{Trifluridine} Cancer} Phase 1.{{Amprenavir} medchemexpress|{Amprenavir} Anti-infection|{Amprenavir} Technical Information|{Amprenavir} References|{Amprenavir} manufacturer|{Amprenavir} Epigenetic Reader Domain}
Formula:
C15H15N7O
Molecular Weight :
309.PMID:24818938 33
Synonyms:
Additional Information:
|CAS No. 1224844-38-5 ; |Formula C15H15N7O ; |Molecular Weight 309.33 ; |SMILES CC(C)[N]1N=C(C2=CC3=C(OC(=N3)N)C=C2)C4=C(N)N=CN=C14 ; |Target mTOR ; |Product Description Sapanisertib (INK 128, MLN0128) is a potent and selective mTOR inhibitor with IC50 of 1 nM in cell-free assays >200-fold less potent to class I PI3K isoforms, superior in blocking mTORC1/2 and sensitive to pro-invasion genes (vs Rapamycin). Phase 1. ; |Purity > 97% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO