Product Name :
SB-505124
CAS No.:
694433-59-5
Purity :
> 98%
Shipping:
Shipped on dry ice.
Storage :
Store at -20 °C. Store under desiccating conditions. The product can be stored for up to 12 months.{{H3B-8800} medchemexpress|{H3B-8800} SF3B1|{H3B-8800} Purity & Documentation|{H3B-8800} Formula|{H3B-8800} supplier|{H3B-8800} Cancer}
SMILES:
CC1=CC=CC(=N1)C2=C(N=C(N2)C(C)(C)C)C3=CC4=C(C=C3)OCO4
Product Description :
SB505124 is a selective inhibitor of TGFβR for ALK4, ALK5 with IC50 of 129 nM and 47 nM in cell-free assays, respectively, also inhibits ALK7, but does not inhibit ALK1, 2, 3, or 6.{{ME-344} site|{ME-344} Metabolic Enzyme/Protease|{ME-344} Purity & Documentation|{ME-344} In stock|{ME-344} custom synthesis|{ME-344} Autophagy}
Formula:
C20H21N3O2
Molecular Weight :
335.40
Synonyms:
Additional Information:
|CAS No. 694433-59-5 ; |Chemical Name 2-[4-(1,3-Benzodioxol-5-yl)-2-(1,1-dimethylethyl)-1H-imidazol-5-yl]-6-methylpyridine ; |Formula C20H21N3O2 ; |Molecular Weight 335.40 ; |PubChem CID 9858940 ; |SMILES CC1=CC=CC(=N1)C2=C(N=C(N2)C(C)(C)C)C3=CC4=C(C=C3)OCO4 ; |Target Kinases ; |Product Description SB505124 is a selective inhibitor of TGFβR for ALK4, ALK5 with IC50 of 129 nM and 47 nM in cell-free assays, respectively, also inhibits ALK7, but does not inhibit ALK1, 2, 3, or 6.PMID:24458656 ; |Purity > 98% ; |Source Synthetic ; |Shipping Shipped on dry ice. ; |Storage Store at -20 °C. Store under desiccating conditions. The product can be stored for up to 12 months. ; |Solubility Overview Soluble in ethanol to 100 mM and in DMSO to 100 mM