Product Name :
Apilimod
CAS No.:
541550-19-0
Purity :
> 97%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
CC1=CC=CC(=C1)\C=N\NC2=CC(=NC(=N2)OCCC3=CC=CC=N3)N4CCOCC4
Product Description :
Apilimod is a cell permeable small molecule that specifically inhibits PIKfyve with an IC50 of 14 nM in an in vitro kinase assay. It is also an inhibitor of IL-12/23 and shows no activity toward other lipid kinases and protein kinases, including PIP4K, PIP5K, mTOR, PI3K and PI4K isoforms.
Formula:
C23H26N6O2
Molecular Weight :
418.{{2680543-57-9} web|{2680543-57-9} Technical Information|{2680543-57-9} In stock|{2680543-57-9} supplier} 49
Synonyms:
STA-5326
Additional Information:
|CAS No. 541550-19-0 ; |Synonyms STA-5326 ; |Formula C23H26N6O2 ; |Molecular Weight 418.49 ; |SMILES CC1=CC=CC(=C1)\C=N\NC2=CC(=NC(=N2)OCCC3=CC=CC=N3)N4CCOCC4 ; |Target mTOR ; |Product Description Apilimod is a cell permeable small molecule that specifically inhibits PIKfyve with an IC50 of 14 nM in an in vitro kinase assay.{{722543-31-9} site|{722543-31-9} Purity & Documentation|{722543-31-9} In Vivo|{722543-31-9} supplier} It is also an inhibitor of IL-12/23 and shows no activity toward other lipid kinases and protein kinases, including PIP4K, PIP5K, mTOR, PI3K and PI4K isoforms.PMID:30726029 ; |Purity > 97% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO