Product Name :
Dinaciclib
CAS No.:
779353-01-4
Purity :
> 98%
Shipping:
Shipped at room temperature.
Storage :
Store at -20 °C. Store under desiccating conditions.
SMILES:
CCC1=C2N=C(C=C(N2N=C1)NCC3=C[N+](=CC=C3)[O-])N4CCCC[C@H]4CCO
Product Description :
Novel, potent, selective cyclin-dependent kinase (CDK) inhibitor displaying selectivity for CDK1, CDK2, CDK5 and CDK9 (IC50 values are 3, 1, 1 and 4 nM respectively). Potent DNA replication inhibitor that blocks thymidine incorporation in A2780 ovarian cancer cells (IC50 = 4 nM).
Formula:
C21H28N6O2
Molecular Weight :
396.49
Synonyms:
SCH 727965, SCH727965
Additional Information:
|CAS No.{{1365803-52-6} medchemexpress|{1365803-52-6} Biological Activity|{1365803-52-6} References|{1365803-52-6} custom synthesis} 779353-01-4 ; |Synonyms SCH 727965, SCH727965 ; |Chemical Name 2-[(2S)-1-[3-ethyl-7-[(1-oxidopyridin-1-ium-3-yl)methylamino]pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-2-yl]ethanol ; |Formula C21H28N6O2 ; |Molecular Weight 396.49 ; |PubChem CID 46926350 ; |SMILES CCC1=C2N=C(C=C(N2N=C1)NCC3=C[N+](=CC=C3)[O-])N4CCCC[C@H]4CCO ; |Product Description Novel, potent, selective cyclin-dependent kinase (CDK) inhibitor displaying selectivity for CDK1, CDK2, CDK5 and CDK9 (IC50 values are 3, 1, 1 and 4 nM respectively).{{981-15-7} medchemexpress|{981-15-7} Purity & Documentation|{981-15-7} Purity|{981-15-7} custom synthesis} Potent DNA replication inhibitor that blocks thymidine incorporation in A2780 ovarian cancer cells (IC50 = 4 nM).PMID:20301652 ; |Format Solid ; |Purity > 98% ; |Source Synthetic ; |Shipping Shipped at room temperature. ; |Storage Store at -20 °C. Store under desiccating conditions. ; |Solubility Overview Soluble in DMSO to 50 mM