Product Name :
Carboxyebselen
Description:
Carboxyebselen (HOOC-Ebs) is a potent and selective inhibitor of endothelial nitric oxide synthase (eNOS).
CAS:
153871-75-1
Molecular Weight:
318.19
Formula:
C14H9NO3Se
Chemical Name:
4-(3-oxo-2,3-dihydro-1,2-benzoselenazol-2-yl)benzoic acid
Smiles :
OC(=O)C1C=CC(=CC=1)N1[Se]C2=CC=CC=C2C1=O
InChiKey:
FOEPTYDLLXMPLJ-UHFFFAOYSA-N
InChi :
InChI=1S/C14H9NO3Se/c16-13-11-3-1-2-4-12(11)19-15(13)10-7-5-9(6-8-10)14(17)18/h1-8H,(H,17,18)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Carboxyebselen (HOOC-Ebs) is a potent and selective inhibitor of endothelial nitric oxide synthase (eNOS).|Product information|CAS Number: 153871-75-1|Molecular Weight: 318.19|Formula: C14H9NO3Se|Chemical Name: 4-(3-oxo-2,3-dihydro-1,2-benzoselenazol-2-yl)benzoic acid|Smiles: OC(=O)C1C=CC(=CC=1)N1[Se]C2=CC=CC=C2C1=O|InChiKey: FOEPTYDLLXMPLJ-UHFFFAOYSA-N|InChi: InChI=1S/C14H9NO3Se/c16-13-11-3-1-2-4-12(11)19-15(13)10-7-5-9(6-8-10)14(17)18/h1-8H,(H,17,18)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Capecitabine} medchemexpress|{Capecitabine} Apoptosis|{Capecitabine} Technical Information|{Capecitabine} In Vitro|{Capecitabine} supplier|{Capecitabine} Epigenetic Reader Domain} |Shelf Life: ≥12 months if stored properly.{{Glycyrrhizic acid} medchemexpress|{Glycyrrhizic acid} Anti-infection|{Glycyrrhizic acid} Purity & Documentation|{Glycyrrhizic acid} In stock|{Glycyrrhizic acid} custom synthesis|{Glycyrrhizic acid} Autophagy} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:33115346 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|Carboxyebselen (HOOC-Ebs), a derivative of Ebselen (Ebs) inhibits NOS present in enzymatic preparations from bovine endothelium, porcine cerebella, and murine spleen, however, it is both more potent and more selective for the constitutive endothelial NOS than Ebs. Unlike Ebs, HOOC-Ebs (0.1-30 microM) causes a concentration-dependent endothelium-independent relaxations of rings of rabbit aorta.|Products are for research use only. Not for human use.|