Product Name :
ML-9
Sequence:
Purity:
≥98% (TLC)
Molecular Weight:
361.3
Solubility :
Soluble in DMSO (10mg/ml) and ethanol/water (1:1, 10mg/ml).
Appearance:
White solid.
Use/Stability :
As indicated on product label or CoA when stored as recommended. Stable for at least 1 year after receipt when stored, as supplied, at 0-4°C. Stock solutions are stable for up to 3 months at -20°C.
Description:
Myelin basic protein inhibitor Selective inhibitor of MLC kinase (Ki=3.8 µM). Inhibits insulin-stimulated 2-deoxyglucose transport and PP-1 activation in adipocytes, possibly via an effect on MAP kinase or its activation. Useful PKB inhibitor (IC50=10-50 µM). Also known to inhibit PKA (IC50=20 µM) and S6 kinase (IC50=50 µM). Does not inhibit PI 3-kinase.
CAS :
105637-50-1
Solubility:
Soluble in DMSO (10mg/ml) and ethanol/water (1:1, 10mg/ml).
Formula:
C15H17N2O2SCl . HCl
Additional Information :
| Alternative Name 1-(5-Chloronaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine .{{1353900-92-1} medchemexpress|{1353900-92-1} Technical Information|{1353900-92-1} In Vitro|{1353900-92-1} manufacturer} HCl | Appearance White solid.{{1854126-41-2} web|{1854126-41-2} Technical Information|{1854126-41-2} Data Sheet|{1854126-41-2} supplier} | CAS 105637-50-1 | Couple Target Akt, MLCK, PKA, S6 kinase | Couple Type Inhibitor | Formula C15H17N2O2SCl .PMID:29494100 HCl | Identity Determined by 1H-NMR and MS. | MW 361.3 | Purity ≥98% (TLC) | Solubility Soluble in DMSO (10mg/ml) and ethanol/water (1:1, 10mg/ml). | Unit of Measure (UM) mg