(41). Weak accountability, including low levels of monitoring, continued from the previous command-and-control system to the new catch hare system, resulting in on-going cheating. In addition, historic overfishing and unprecedented warming of the Northwest Atlantic have resulted in slow recovery and changing baselines for some of the iconic, high-profile stocks (50). Multiple lessons emerge from these collective experiences. The design of a catch hare program matters. Accountability by fishers and good monitoring are key. Transition, implementation, and compliance costs are real and must be dealt with, ideally from the outset. Allocation must be sensitive to a range of considerations, including equity. The West Coast IFQ groundfish fishery and the Gulf of Mexico red snapper commercial fishery RBF programs both took years to design, and benefited from abundant earlier lessons. And all fisheries must be managed in light of escalating impacts of climate changes and ocean CEP-37440 custom synthesis acidification. Today, fisheries overall in the United States are improving dramatically (36?8). Around 65 by volume of the fish caught in United States federal waters are under a RBF fishery management system (51). The overall effectiveness of management, and resulting condition of fish stocks, is high and improving each year, with a dramatic decrease in overfished stocks and continuing strong improvements in the federal fish stock sustainability index (51, 52). RBF management continues to make an important contribution to this turnaround. At the global scale, today there are over 200 RBFs covering over 500 species in 40 countries (53). After 40 y of trial-anderror, RBFs are now gaining traction as the benefits of changing incentives for fishers become better known and are realized, and as lessons accrue about how to tailor the design of any particular RBF system to meet a combination of social, ecological, and economic goals. RBFs are also recognized as an effective pathway to eco-certification (54). RBFs are not a panacea, and each must be designed appropriately for the local conditions. Good science and strong community engagement are essential to enable the success of the RBF approach, including setting appropriate science-based catch limits. Another form of secure-access fishery management is with territorial-use rights in fisheries (TURFs). TURFs are used increasingly, especially in developing countries, and are leading to beneficial outcomes for fishers because they create or strengthen feedbacks that lead to sustainability. TURFs assign spatial fishing rights to individuals or communities and provide fishers with secure access to a portion of the total fishery. 4-Hydroxytamoxifen biological activity Recent work in Belize (55) has shown that when TURFs are paired with marine reserves (i.e., areas where no fishing or other extractive activities are allowed), fishers can take advantage of the spillover of fish from the reserves. This process leads to increases in catch and profit while also conserving important habitat and providing a refuge for fish (55, 56). Known as a TURF-reserve, the pairing of secure-access fishing rights with marine reserves creates economic incentives for fishers to be stewards of their own fishing area, not overfish, and reduce illegal fishing. Following implementation, Belize saw a 60 decline in violations of fishing regulations (56). In addition, the TURF-reserve strengthens personally motivated incentives for ocean stewardship by sustaining cultural values, as well as commun.(41). Weak accountability, including low levels of monitoring, continued from the previous command-and-control system to the new catch hare system, resulting in on-going cheating. In addition, historic overfishing and unprecedented warming of the Northwest Atlantic have resulted in slow recovery and changing baselines for some of the iconic, high-profile stocks (50). Multiple lessons emerge from these collective experiences. The design of a catch hare program matters. Accountability by fishers and good monitoring are key. Transition, implementation, and compliance costs are real and must be dealt with, ideally from the outset. Allocation must be sensitive to a range of considerations, including equity. The West Coast IFQ groundfish fishery and the Gulf of Mexico red snapper commercial fishery RBF programs both took years to design, and benefited from abundant earlier lessons. And all fisheries must be managed in light of escalating impacts of climate changes and ocean acidification. Today, fisheries overall in the United States are improving dramatically (36?8). Around 65 by volume of the fish caught in United States federal waters are under a RBF fishery management system (51). The overall effectiveness of management, and resulting condition of fish stocks, is high and improving each year, with a dramatic decrease in overfished stocks and continuing strong improvements in the federal fish stock sustainability index (51, 52). RBF management continues to make an important contribution to this turnaround. At the global scale, today there are over 200 RBFs covering over 500 species in 40 countries (53). After 40 y of trial-anderror, RBFs are now gaining traction as the benefits of changing incentives for fishers become better known and are realized, and as lessons accrue about how to tailor the design of any particular RBF system to meet a combination of social, ecological, and economic goals. RBFs are also recognized as an effective pathway to eco-certification (54). RBFs are not a panacea, and each must be designed appropriately for the local conditions. Good science and strong community engagement are essential to enable the success of the RBF approach, including setting appropriate science-based catch limits. Another form of secure-access fishery management is with territorial-use rights in fisheries (TURFs). TURFs are used increasingly, especially in developing countries, and are leading to beneficial outcomes for fishers because they create or strengthen feedbacks that lead to sustainability. TURFs assign spatial fishing rights to individuals or communities and provide fishers with secure access to a portion of the total fishery. Recent work in Belize (55) has shown that when TURFs are paired with marine reserves (i.e., areas where no fishing or other extractive activities are allowed), fishers can take advantage of the spillover of fish from the reserves. This process leads to increases in catch and profit while also conserving important habitat and providing a refuge for fish (55, 56). Known as a TURF-reserve, the pairing of secure-access fishing rights with marine reserves creates economic incentives for fishers to be stewards of their own fishing area, not overfish, and reduce illegal fishing. Following implementation, Belize saw a 60 decline in violations of fishing regulations (56). In addition, the TURF-reserve strengthens personally motivated incentives for ocean stewardship by sustaining cultural values, as well as commun.