These enzymes catalyze the Amadori rearrangements of different substrates ProFAR and PRA by very similar mechanisms [63,sixty four]. These substrates share a ribose-five-phosphate moiety, and ProFAR has an extra ribose related by imidazole and PRA has an anthranilate moiety
The distribution of active internet site residues at the stop of eight b-strands of enzymes in the superfamilies adopting the TIM barrel fold. White bars represent the glycosidase superfamily (CATH…